Retooling Pap test to spot more kinds of cancer


WASHINGTON (AP) — For years, doctors have lamented that there's no Pap test for deadly ovarian cancer. Wednesday, scientists reported encouraging signs that one day, there might be.


Researchers are trying to retool the Pap, a test for cervical cancer that millions of women get, so that it could spot early signs of other gynecologic cancers, too.


How? It turns out that cells can flake off of tumors in the ovaries or the lining of the uterus, and float down to rest in the cervix, where Pap tests are performed. These cells are too rare to recognize under the microscope. But researchers from Johns Hopkins University used some sophisticated DNA testing on the Pap samples to uncover the evidence — gene mutations that show cancer is present.


In a pilot study, they analyzed Pap smears from 46 women who already were diagnosed with either ovarian or endometrial cancer. The new technique found all the endometrial cancers and 41 percent of the ovarian tumors, the team reported Wednesday in the journal Science Translational Medicine.


This is very early-stage research, and women shouldn't expect any change in their routine Paps. It will take years of additional testing to prove if the so-called PapGene technique really could work as a screening tool, used to spot cancer in women who thought they were healthy.


"Now the hard work begins," said Hopkins oncologist Dr. Luis Diaz, whose team is collecting hundreds of additional Pap samples for more study and is exploring ways to enhance the detection of ovarian cancer.


But if it ultimately pans out, "the neat part about this is, the patient won't feel anything different," and the Pap wouldn't be performed differently, Diaz added. The extra work would come in a lab.


The gene-based technique marks a new approach toward cancer screening, and specialists are watching closely.


"This is very encouraging, and it shows great potential," said American Cancer Society genetics expert Michael Melner.


"We are a long way from being able to see any impact on our patients," cautioned Dr. Shannon Westin of the University of Texas MD Anderson Cancer Center. She reviewed the research in an accompanying editorial, and said the ovarian cancer detection would need improvement if the test is to work.


But she noted that ovarian cancer has poor survival rates because it's rarely caught early. "If this screening test could identify ovarian cancer at an early stage, there would be a profound impact on patient outcomes and mortality," Westin said.


More than 22,000 U.S. women are diagnosed with ovarian cancer each year, and more than 15,000 die. Symptoms such as pain and bloating seldom are obvious until the cancer is more advanced, and numerous attempts at screening tests have failed.


Endometrial cancer affects about 47,000 women a year, and kills about 8,000. There is no screening test for it either, but most women are diagnosed early because of postmenopausal bleeding.


The Hopkins research piggybacks on one of the most successful cancer screening tools, the Pap, and a newer technology used along with it. With a standard Pap, a little brush scrapes off cells from the cervix, which are stored in a vial to examine for signs of cervical cancer. Today, many women's Paps undergo an additional DNA-based test to see if they harbor the HPV virus, which can spur cervical cancer.


So the Hopkins team, funded largely by cancer advocacy groups, decided to look for DNA evidence of other gynecologic tumors. It developed a method to rapidly screen the Pap samples for those mutations using standard genetics equipment that Diaz said wouldn't add much to the cost of a Pap-plus-HPV test. He said the technique could detect both early-stage and more advanced tumors. Importantly, tests of Paps from 14 healthy women turned up no false alarms.


The endometrial cancers may have been easier to find because cells from those tumors don't have as far to travel as ovarian cancer cells, Diaz said. Researchers will study whether inserting the Pap brush deeper, testing during different times of the menstrual cycle, or other factors might improve detection of ovarian cancer.


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Venezuela postpones inauguration for cancer-stricken Chavez


CARACAS (Reuters) - Venezuela will postpone the inauguration of President Hugo Chavez for a new term due to health problems, the government said on Tuesday, another sign the socialist leader's cancer may be bringing an end to his 14 years in power.


The 58-year-old former soldier who has dominated the South American OPEC nation since 1999 has not been heard from since surgery on December 11 in Cuba - his fourth operation since he was diagnosed with an undisclosed type of cancer in June 2011.


The announcement outraged opposition leaders who insist that Chavez must be sworn in before the National Assembly on January 10 as laid out in the constitution, or temporarily step aside and leave an ally in power.


"The commander president wants us to inform that, based on his medical team's recommendations, the post-operative recovery should extend past January 10," said Vice President Nicolas Maduro, Chavez's chosen successor, in a letter read to the legislature.


"As a result, he will not be able to be present at the National Assembly on that date."


The letter said authorities would seek another date for the inauguration ceremony but did not say when it would take place or give a time frame for Chavez's return from Havana.


Rather than being sworn in by the legislature, he would take his oath at a later date before the Supreme Court, the letter said, as allowed by the constitution.


Government leaders insist Chavez is completely fulfilling his duties as head of state, even though official medical bulletins say he has a severe pulmonary infection and has had trouble breathing.


The government has called for a massive rally outside the presidential palace on Thursday, and allied presidents including Uruguay's Jose Mujica and Bolivia's Evo Morales have confirmed they will visit Venezuela this week despite Chavez's absence.


Argentine President Cristina Fernandez has announced plans to visit Chavez in Havana on Friday.


But the unprecedented silence by the president - famous for regularly speaking for hours in meandering broadcasts - has left many convinced he could be in his last days.


His resignation or death would upend politics in the oil-rich nation, where he enjoys a deity-like status among poor supporters thankful for his social largesse.


His critics call him a fledgling dictator who has squandered billions of dollars from crude sales while dashing the independence of state institutions.


CONSTITUTION DISPUTE


The constitution does not specify what happens if the president does not take office on January 10.


The Supreme Court, controlled by Chavez allies, called a news conference for Wednesday. It is widely expected to announce an interpretation of the constitution that will give Chavez leeway to take office when he is fit to do so.


If he dies or steps aside, new elections would be called within 30 days. Before leaving for Havana in December, the president instructed his supporters to back Maduro in that vote if he were unable to continue.


Opposition leaders argue that Congress chief and Chavez ally Diosdado Cabello should take over, as mandated by the constitution if the president's absence is formally declared.


Cabello has ruled that out, saying the president continues to be in charge.


"Who could have believed the opposition would be screaming for Diosdado Cabello to be given the presidency of the republic?" he said during a rambunctious session of Congress. "That's crazy, the opposition is losing it."


Meanwhile opposition deputies accused the Socialist Party of failing to follow Chavez's instructions - a scene that would have been unimaginable before Chavez's prolonged absence.


"President Chavez is the only one among you who has spoken clearly," said opposition leader Julio Borges.


He was drowned out by pro-Chavez deputies clapping and chanting the socialist leader's name and rebuffed by Cabello, who had long been considered a potential successor to Chavez until he was passed over for Maduro.


"It's not my fault you weren't chosen, don't take your frustration out on me," Borges quipped.


Another opposition deputy complained that during the debate a copy of the constitution was thrown across the chamber from the direction of the Socialist Party's deputies.


Chavez's supporters have held near-daily vigils for his recovery, while opposition activists accuse the president's allies of a Cuban-inspired manipulation of the situation.


Maduro has taken over the day-to-day running of the government and looks set to continue in the role past Thursday.


The mustachioed former bus driver lacks Chavez's charisma, but he has sought to imitate the president's style with vituperative attacks on the opposition and televised ribbon-cutting ceremonies.


With the micro-managing Chavez away, major policy decisions in Venezuela, such as a widely expected devaluation of the bolivar currency, appear to be on hold.


Venezuelan bond prices, which had soared in recent weeks on Chavez's health woes, dipped on Monday and Tuesday as investors' expectations of a quick government change apparently dimmed.


"The 'regime change' euphoria seems excessive taking into account the unclear legal transition and perhaps, more importantly, the risk that regime change does not allow for policy change," New York-based Jefferies' managing director Siobhan Morden said in a note on the bonds.


(Editing by Daniel Wallis and Eric Beech)



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Malaysian manhunt on as escape drama spices up






KUALA LUMPUR: Seven Malaysians who escaped police custody this week did so by temporarily blinding a guard with chilli powder hidden in one of the escapee's underpants, police and press reports said Wednesday.

The escape Monday of the seven men -- whom police have called "dangerous criminals" -- has prompted a large-scale manhunt in the northern Malaysian state of Penang.

But the seven escapees remained at large after their daring break-out from a police van as they were being transported to a local court.

The detainees had staged a fight in the vehicle, prompting its driver to pull over, police said.

When the police opened the rear door to investigate, "they threw chilli powder on a policeman", Abdul Rahman Ibrahim, a local police official, told AFP, as other detainees attacked and injured his fellow guards.

Abdul Rahman declined to elaborate on the use of the spices, but press reports have said one of the men had concealed the chilli powder in his underwear.

Chilli powder is ubiquitous in Malaysia, which is known for its spicy cuisine.

The seven fugitives then sped off in the police van, which was later found abandoned in a nearby village, police have said.

Some 250 police officers aided by tracker dogs and a police helicopter were scouring the area near where the van was discarded, said Abdul Rahim Hanafi, Penang's state police chief.

"The escapees are dangerous criminals who have been charged with serious offences, including murder, gang robbery and causing grievous hurt," he was quoted as saying by The Star newspaper.

Police were investigating how the detainees had obtained the chilli powder.

The Star quoted an unnamed source saying the powder could have been from the spicy seasoning sachets found in instant noodle packets that are sometimes provided to detainees by family members during visits.

- AFP/al



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Guns fall silent on LoC

JAMMU: The Line of Control in Jammu and Kashmir was calm on Wednesday morning after overnight clashes between Indian and Pakistan troops, military officials said.

Pakistani guns fell silent in Krishnaghati sector in Poonch district, even as the Indian Army stepped up vigil all along the ​Line of Control (LoC) after Pakistani troops entered Indian territory and killed two Indian soldiers Tuesday.

On Tuesday evening, the Pakistani army opened fire on Indian posts in Krishnaghati sector, about 230 km from Jammu. The losses, if any, were not immediately known.

Indian officials accused the Pakistani soldiers of mutilating one of the two dead soldiers besides wounding a third Tuesday.

Islamabad says it was not involved in the attack, suggesting it could be the work of separatist militants.

Military sources said the Indian Army was prepared to give a "calibrated response" to any further provocation from Pakistan.

"There was heavy firing from the Pakistani side last night. We offered calibrated response and the guns fell silent by midnight," an army officer told IANS Wednesday morning.

"At the moment the LoC is calm," he added.

The LoC divides the Kashmir region between India and Pakistan. New Delhi controls the southern two-third of Kashmir and Islamabad the northern third.

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Report: Death rates from cancer still inching down


WASHINGTON (AP) — Death rates from cancer are continuing to inch down, researchers reported Monday.


Now the question is how to hold onto those gains, and do even better, even as the population gets older and fatter, both risks for developing cancer.


"There has been clear progress," said Dr. Otis Brawley of the American Cancer Society, which compiled the annual cancer report with government and cancer advocacy groups.


But bad diets, lack of physical activity and obesity together wield "incredible forces against this decline in mortality," Brawley said. He warned that over the next decade, that trio could surpass tobacco as the leading cause of cancer in the U.S.


Overall, deaths from cancer began slowly dropping in the 1990s, and Monday's report shows the trend holding. Among men, cancer death rates dropped by 1.8 percent a year between 2000 and 2009, and by 1.4 percent a year among women. The drops are thanks mostly to gains against some of the leading types — lung, colorectal, breast and prostate cancers — because of treatment advances and better screening.


The news isn't all good. Deaths still are rising for certain cancer types including liver, pancreatic and, among men, melanoma, the most serious kind of skin cancer.


Preventing cancer is better than treating it, but when it comes to new cases of cancer, the picture is more complicated.


Cancer incidence is dropping slightly among men, by just over half a percent a year, said the report published by the Journal of the National Cancer Institute. Prostate, lung and colorectal cancers all saw declines.


But for women, earlier drops have leveled off, the report found. That may be due in part to breast cancer. There were decreases in new breast cancer cases about a decade ago, as many women quit using hormone therapy after menopause. Since then, overall breast cancer incidence has plateaued, and rates have increased among black women.


Another problem area: Oral and anal cancers caused by HPV, the sexually transmitted human papillomavirus, are on the rise among both genders. HPV is better known for causing cervical cancer, and a protective vaccine is available. Government figures show just 32 percent of teen girls have received all three doses, fewer than in Canada, Britain and Australia. The vaccine was recommended for U.S. boys about a year ago.


Among children, overall cancer death rates are dropping by 1.8 percent a year, but incidence is continuing to increase by just over half a percent a year. Brawley said it's not clear why.


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Holmes Played Childish Games After Aurora Carnage













As police confronted the movie theater carnage and a massive booby trap left behind by accused Aurora gunman James Holmes, the suspect loopily played with hand puppets, tried to stick a metal staple in an electrical socket and clamly flipped a styrofoam cup, according to court testimony today.


Holmes, 25, displayed the bizarre behavior once he was in custody and taken to Aurora police headquarters after the shooting that left 12 people dead and dozens injured, the lead investigator in the case testified today.


While being cross examined by Colorado public defender Daniel King, Police Detective Craig Appel was asked about the observations of two Aurora officers assigned to watch over Holmes in an interrogation room.


Appel said that to preserve possible gunshot residue, police had placed paper bags over Holmes' hands. One officer, King said, noted in a report that Holmes began moving his hands "in a talking puppet motion."


Click here for full coverage of the Aurora movie theater shooting.


King asked if Appel was also aware that the officer "observed Holmes take a staple out of the table and tried to stick it in an electrical socket?" Appel confirmed Holmes' actions.








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The officers also noted that they watched as Holmes began playing with an empty styrofoam cup, trying to "flip it" on the table.


While Holmes was carrying out his childish antics, police were puzzling over a complex booby trap Holmes had left behind in his apartment, according to testimony.


A gasoline-soaked carpet, loud music and a remote control car were part of Holmes' plan to trick someone into triggering a blast that would destroy his apartment and lure police to the explosion while he shot up a movie theater in Aurora, Colo., according to court testimony.


FBI agent Garrett Gumbinner told the court that he interviewed Holmes on July 20, hours after he killed 12 and wounded 58 during the midnight showing of "The Dark Knight Rises."


"He said he rigged the apartment to explode to get law enforcement to send resources to his apartment instead of the theater," Gumbinner said.


His plan failed to prompt someone into triggering the bombs.


Gumbinner said Holmes had created two traps that would have set off the blast.


The apartment was rigged with a tripwire at the front door connected to a mixture of chemicals that would create heat, sparks and flame. Holmes had soaked the carpet with a gasoline mixture that was designed to be ignited by the tripwire, Gumbinner said.


"It would have caused fire and sparks," the agent said, and "would have made the entire apartment explode or catch fire."


Holmes had set his computer to play 25 minutes of silence followed by loud music that he hoped would cause a disturbance loud enough that someone would call police, who would then respond and set off the explosion by entering the apartment.


Gumbinner said Holmes also told him he rigged a fuse between three glass jars that would explode. He filled the jars with a deadly homemade chemical mixture that would burn so hot it could not be extinguished with water.






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In India, questions over decision to treat rape victim overseas


NEW DELHI (Reuters) - The decision to fly the victim of a gang rape that outraged India for treatment in Singapore made little medical sense as the woman was so severely injured that her death was all but inevitable, doctors say.


The government, on the back foot after furious street protests and stinging criticism of authorities over the December 16 rape in the capital, New Delhi, has struggled to defend its decision to send the 23-year-old physiotherapy student overseas. She died 48 hours later.


With a deadly infection seeping into her blood from damage done to her intestines during the assault, complicated by a cardiac arrest and damage to the brain, she was just clinging to life when she was flown 2,500 miles from New Delhi to Singapore late on December 26, doctors said.


"It was ethically and morally wrong to have taken her out, given that she was sinking and her chances of survival were next to zero at that stage," said a doctor at New Delhi's All India Institute of Medical Sciences (AIIMS), which was advising the team treating the woman at a sister hospital across the street.


"Such a thing raises false hopes in the minds of the family, the community. No doctor in his right mind would do this, unless you want to get the patient off your back," said the doctor, who declined to be identified, saying colleagues at the government-run hospital who had spoken out had been warned of consequences in what has become a politically explosive case.


The woman, who was assaulted by five men and a teenager on a moving bus after a male companion was beaten unconscious, cannot be named under an Indian law that prohibits identifying victims of rape.


Another doctor who was consulted during the woman's care at New Delhi's Safdarjang hospital, where she was taken following the assault, said she had been getting the best possible treatment in India and the question of why she was shifted should be answered by the government.


Many security officials have said they feared the protests would escalate if the woman had died in New Delhi, but the government has said the only consideration was her wellbeing.


"The idea was to give her the best possible treatment," said Harish Rawat, a government minister who attended a cabinet meeting on the woman's condition and the efforts to save her.


"I don't think the idea was to run away from the problem. Death here or death abroad would still have the same impact," he said. "We felt if there was a chance to save her, it should be tried. Take her to a transplant facility abroad."


At the time of the transfer, authorities at Safdarjang said her condition was critical which was why they decided to move her to Singapore's Mount Elizabeth Hospital, which specialized in multi-organ transplant.


But a transplant for her damaged intestine, if at all possible, was months away, doctors said. At the time of her transfer, the woman, unconscious since a heart attack the previous night, was in no condition to go through such an operation.


"One cannot think about intestinal transplant at this moment," Samiran Nundy, the head of surgical gastroenterology and organ transplantation at the Ganga Ram Hospital in New Delhi, was quoted as saying in newspapers.


"First, the infection spreading in her should be stopped, then one can think about transplant."


Within 40 hours of her arrival in Singapore, doctors called her family and told them the end was near, even as millions prayed at home in the hope that she would pull through.


"Sepsis followed by cardiac arrest is a terminal event in 99 percent of cases," said the doctor at AIIMS, referring to blood infection.


"Doctors will have anecdotal evidence about one or two cases in their whole career of somebody who survived. I had one case, a woman, but she too died within a month. Yes, miracles happen, but you were not looking at one in this case. It was clear to everyone, especially after the cardiac arrest."


PROTESTS AND PANIC


Piecing together the events leading up to her death tells a tale of authorities in Delhi trying to defuse public anger over the attack by initially insisting that she was getting the best possible treatment, and then, as things began to go wrong, getting increasingly worried that the protests that tapped a deep vein of frustration, could spin out of control.


The alarm bells for the government rang late on Christmas night when the woman suffered the cardiac arrest. That was nine days after she was brought in to Safdarjang hospital in a life-threatening condition after the brutal assault - she was assessed then as 5 on a scale in which 6 is rated as no chance of survival.


After the heart attack, her pulse rate became critically low. Doctors resuscitated her after three to four minutes but by then she had become unconscious, caused by lack of blood to the brain. She never regained consciousness from that point on.


Equally worrisome, the infection from her injured intestines had seeped into her blood and was spreading to her vital organs.


For the government, shaken by the scale and intensity of the protests that focused on the lack of safety in the capital for women, the deterioration in her health was cause for concern.


Even as the federal cabinet met the next morning, arrangements to fly the woman for treatment in Singapore were being put in place.


One official said the public mood was so fragile that the government felt that if she died in India, some people would have blamed the government for not sending her abroad for treatment.


"You can argue this the other way. They would have said 'if Sonia can go abroad, why not this girl'," the official said, referring to the head of the ruling Congress party, Sonia Gandhi, who travels abroad for treatment of an undisclosed condition.


Outside the prime minister's office where the cabinet met, thousands of baton-wielding police including crack members of Rapid Action Force kept the area under a lockdown. Days earlier, pitched battles broke out between hundreds of protesters and police at the scene, in which a policeman was killed.


Protesters had climbed the walls of South and North Block, the high-security seat of government, while others swarmed towards the iron gates of the presidential palace. They carried placards such as "The only two women safe in Delhi are Sonia Gandhi and Sheila Dikshit". Dikshit is the chief minister, the top elected official of the local government of Delhi.


A government official privy to the handling of the protests said the administration had not anticipated that so many students would come out onto the streets and that the protests would last for so many days.


But when protesters showed up at the presidential palace, the line had been crossed in the security agencies' mind.


"It was a near-breach of security at the presidential palace. The officials tasked with security didn't know how to control the protesters, if they had jumped over its gates. Would you fire at the students, the housewives?" the official asked.


The Intelligence Bureau, which coordinates all domestic intelligence, had been warning that the public mood may turn uglier, the official said.


NO PASSPORTS


At Safdarjung on the morning of December 26, a team of doctors arrived from Medanta Medicity, a private medical centre which runs an air ambulance service. Their mandate was to assess whether she could survive the airlift, said Dr Yatin Mehta, head of critical care at Medicity.


"The decision was to take her out of the country. Our job was to determine whether she could take the airlift, not whether she should be going or not," said Mehta, who accompanied the woman on the flight.


He said the option of sending her to Cambridge in Britain to a hospital that specializes in transplants, was considered but dropped because it would have involved a refueling stop for the aircraft and a two-hour road trip upon landing in London.


Flying her to the Canadian city of Toronto, which also has a specialized organ transplant centre, was also vetoed. They zeroed in on Singapore, six hours flying time away.


It is highly unusual for someone to be flown out of India for critical care. If anything, the traffic is the reverse, with people travelling to the country for treatment.


In the event, the transfer to Singapore was successful, Mehta said, although the woman suffered a drop in blood pressure during the flight. "We were prepared for that. We handed her over to Mount E in the same condition she left the hospital in Delhi," he said, referring to the Singapore hospital.


The woman's family first got wind of the plan to transfer her at hospital in Delhi, when her brother noticed a flurry of activity and a staff member said that doctors were considering moving her.


"We accepted the decision. We were not interfering in the treatment. The doctors said it was in the best interest of our sister, we accepted it. Our only condition was to save her," the brother told Reuters.


Shortly afterwards, officials from the foreign ministry arrived and issued the family travel documents, since none of them had a passport. Their pictures were taken at the hospital.


Three ambulances arrived at the hospital. One of the ambulances headed into the interior of the city and another took the route to the Medanta centre, followed by a convoy of television crews.


A third, carrying the woman, sped away to a special section of Delhi airport, giving everyone the slip.


After she was taken to Singapore, authorities in the city-state's Mount Elizabeth Hospital were frank about her bleak chances for survival.


"The patient is currently struggling against the odds, and fighting for her life," Chief Executive Officer Kelvin Loh said in a statement a day after she was admitted.


"Our medical team's investigations upon her arrival at the hospital yesterday showed that in addition to her prior cardiac arrest, she also had infection of her lungs and abdomen as well as significant brain injury."


Later that day, Soh said her condition was deteriorating.


Her family was told the end was near.


"We didn't expect her to go so quickly," said her brother, who was with her when she died. "At 9:30 p.m., the doctors called us in and said they were sorry, they couldn't do anything more. Her vital organs were failing."


"We went inside and stayed with her the whole night. We saw her heart beat slowing down on the machine. It kept dropping and then dropped to zero. The time was 4:05 a.m."


(Additional reporting by Rajesh Kumar Singh in New Delhi and Kevin Lim in Singapore; Editing by Robert Birsel and Raju Gopalakrishnan)



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Private newspapers in Myanmar gearing up for the daily grind






YANGON: Private newspapers in Myanmar are gearing up to publish dailies for the first time, after authorities indicated they would begin issuing such licences in April.

Currently, only state-owned newspapers are allowed to publish dailies -- private ones are restricted to weeklies.

But observers caution that the still under-developed Myanmar economy might prove a challenge for private dailies.

There was a time when journalists from private newspapers like The Myanmar Times had to subject their reports to government censorship before the papers could be sent to the printers. But that changed last August, when authorities began reforming Myanmar's media regulations.

Geoffrey Goddard, senior editor of The Myanmar Times, said: "It was the curse of our professional lives and there was much celebration in the fourth estate when the decision was made by the government as part of the reform process to end pre-publication censorship."

Now, the government has indicated it will further liberalise the media sector -- by allowing applications for private daily licences as early as next month.

Mr Goddard added: "What we are eagerly looking forward to is the granting of licences to publish daily. That's the next big challenge for us and other newspapers in Myanmar."

The Myanmar Times has shown an interest in getting the license. But as with the rest of the world, the dailies have to contend with the onslaught of the online media. Currently, the Myanmar internet infrastructure might still be in the 90s, but it is expected to get up to speed soon.

There are more than 300 private weekly journals currently being published in Myanmar -- less than five are in English.

While many are excited at the prospect of publishing daily, observers doubt the viability of private dailies, given the country's under-developed economy.

Myo Aung, managing director of Success International Distributor, said: "Compared to neighbouring countries, our advertising budget is not very big. Most are local products. They advertise in magazines, journals and newspapers.

"But we hope that the government allows foreign investors to invest here. If foreign investors, and foreign firms and foreign expertise are here, I think our advertising scenario will also change very soon."

The government has already allowed foreign dailies to be distributed in the country.

And with the three state-controlled dailies currently having a circulation of 2.5 million copies a day, it will be a tough environment for upcoming private ones to compete in.

-CNA/ac



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Jharkhand cabinet recommends dissolution of assembly

RANCHI: The Jharkhand cabinet on Tuesday recommended the dissolution of the state assembly a day after Jharkhand Mukti Morcha (JMM) withdrew its support to the BJP-led government, said an official.

The cabinet meeting was attended by ministers from the BJP, All Jharkhand Students Union and Janata Dal-United. JMM ministers did not attend the meeting, said the official in the chief minister's office.

The cabinet's decision comes ahead of JMM presenting the letter of withdrawal of support to the governor.

The withdrawal of support on Monday has reduced the state government to a minority in the 82-member assembly.

Relations between JMM and BJP have been strained ever since chief minister Arjun Munda denied there was an agreement between the two parties on sharing the chief minister's post.

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Report: Death rates from cancer still inching down


WASHINGTON (AP) — Death rates from cancer are continuing to inch down, researchers reported Monday.


Now the question is how to hold onto those gains, and do even better, even as the population gets older and fatter, both risks for developing cancer.


"There has been clear progress," said Dr. Otis Brawley of the American Cancer Society, which compiled the annual cancer report with government and cancer advocacy groups.


But bad diets, lack of physical activity and obesity together wield "incredible forces against this decline in mortality," Brawley said. He warned that over the next decade, that trio could surpass tobacco as the leading cause of cancer in the U.S.


Overall, deaths from cancer began slowly dropping in the 1990s, and Monday's report shows the trend holding. Among men, cancer death rates dropped by 1.8 percent a year between 2000 and 2009, and by 1.4 percent a year among women. The drops are thanks mostly to gains against some of the leading types — lung, colorectal, breast and prostate cancers — because of treatment advances and better screening.


The news isn't all good. Deaths still are rising for certain cancer types including liver, pancreatic and, among men, melanoma, the most serious kind of skin cancer.


Preventing cancer is better than treating it, but when it comes to new cases of cancer, the picture is more complicated.


Cancer incidence is dropping slightly among men, by just over half a percent a year, said the report published by the Journal of the National Cancer Institute. Prostate, lung and colorectal cancers all saw declines.


But for women, earlier drops have leveled off, the report found. That may be due in part to breast cancer. There were decreases in new breast cancer cases about a decade ago, as many women quit using hormone therapy after menopause. Since then, overall breast cancer incidence has plateaued, and rates have increased among black women.


Another problem area: Oral and anal cancers caused by HPV, the sexually transmitted human papillomavirus, are on the rise among both genders. HPV is better known for causing cervical cancer, and a protective vaccine is available. Government figures show just 32 percent of teen girls have received all three doses, fewer than in Canada, Britain and Australia. The vaccine was recommended for U.S. boys about a year ago.


Among children, overall cancer death rates are dropping by 1.8 percent a year, but incidence is continuing to increase by just over half a percent a year. Brawley said it's not clear why.


Read More..